Dr Carolin Kosiol


Dyers Brae 3
tel. 01334 463598
fax. 01334 463366

My work focuses on the development of computational methods to the investigate the process of adaptation at different time-scales ranging from a few generations in experimental evolution data to phylogenetic analysis of multiple species diverged millions of years ago. In particular, we are interested in DNA sequence evolution by mutation and shifts of allele frequencies.



Rogers, J, Raveendran, M, Harris, RA, Mailund, T, Leppälä, K, Athanasiadis, G, Schierup, MH, Cheng, J, Munch, K, Walker, JA, Konkel, MK, Jordan, V, Steely, CJ, Beckstrom, TO, Bergey, C, Burrell, A, Schrempf, D, Noll, A, Kothe, M, Kopp, GH, Liu, Y, Murali, S, Billis, K, Martin, FJ, Muffato, M, Cox, L, Else, J, Disotell, T, Muzny, DM, Phillips-conroy, J, Aken, B, Eichler, EE, Marques-bonet, T, Kosiol, C, Batzer, MA, Hahn, MW, Tung, J, Zinner, D, Roos, C, Jolly, CJ, Gibbs, RA & Worley, KC 2019, 'The comparative genomics and complex population history of Papio baboons' Science Advances, vol. 5, no. 1, eaau6947. DOI: 10.1126/sciadv.aau6947
Bergman, J, Schrempf, D, Kosiol, C & Vogl, C 2018, 'Inference in population genetics using forward and backward, discrete and continuous time processes' Journal of Theoretical Biology, vol. 439, pp. 166-180. DOI: 10.1016/j.jtbi.2017.12.008
Bertl, J, Ewing, G, Kosiol, C & Futschik, A 2017, 'Approximate maximum likelihood estimation for population genetic inference' Statistical Applications in Genetics and Molecular Biology, vol. 16, no. 5-6, pp. 291-312. DOI: 10.1515/sagmb-2017-0016
Balao, F, Trucchi, E, Wolfe, T, Hao, B-H, Lorenzo, MT, Baar, J, Sedman, L, Kosiol, C, Amman, F, Chase, MW, Hedrén, M & Paun, O 2017, 'Adaptive sequence evolution is driven by biotic stress in a pair of orchid species (Dactylorhiza) with distinct ecological optima' Molecular Ecology, vol. 26, no. 14, pp. 3649-3662. DOI: 10.1111/mec.14123
Schrempf, D, Minh, BQ, De Maio, N, von Haeseler, A & Kosiol, C 2016, 'Reversible polymorphism-aware phylogenetic models and their application to tree inference' Journal of Theoretical Biology, vol. 407, pp. 362-370. DOI: 10.1016/j.jtbi.2016.07.042
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