Prof Terry Smith

Professor

BMS B310
tel. 01334-463412
fax. 01334 462595
tks1@st-andrews.ac.uk

Professor Terry K. Smith is a reader in both the school of chemistry and the school of biology at the University of St Andrews, Scotland. His research utilizes a wide range of disciplines to genetically and chemically validate drug targets involved in lipid metabolism of protozoan parasites that cause neglected tropical diseases such as African sleeping sickness and American Trypanosomiasis.

An interview with Terry by the International Innovation magazine can be found here.

 

Publications

Kipandula, W, Young, SA, MacNeill, SA & Smith, TK 2018, 'Screening of the MMV and GSK open access chemical boxes using a viability assay developed against the kinetoplastid Crithidia fasciculata' Molecular and Biochemical Parasitology, vol In press. DOI: 10.1016/j.molbiopara.2018.05.001
Ashok, P, Chander, S, Smith, TK & Sankaranarayanan, M 2018, 'Design, synthesis and biological evaluation of piperazinyl-β-carbolinederivatives as anti-leishmanial agents' European Journal Of Medicinal Chemistry, vol 150, pp. 559-566. DOI: 10.1016/j.ejmech.2018.03.022
Fraser, AL, Menzies, SK, King, EFB, Tulloch, L, Gould, ER, Zacharova, M, Smith, TK & Florence, GJ 2018, 'Design and synthesis of broad spectrum trypanosomatid selective inhibitors' ACS Infectious Diseases, vol 4, no. 4, pp. 560-567. DOI: 10.1021/acsinfecdis.7b00187
Ooi, C-P, Smith, TK, Gluenz, E, Wand, NV, Vaughan, S & Rudenko, G 2018, 'Blocking variant surface glycoprotein synthesis alters endoplasmic reticulum exit sites/Golgi homeostasis in Trypanosoma brucei' Traffic, vol Early View. DOI: 10.1111/tra.12561
Ronin, C, Costa, DM, Tavares, J, Faria, J, Ciesielski, F, Ciapetti, P, Smith, TK, MacDougall, J, Cordeiro-da-Silva, A & Pemberton, IK 2018, 'The crystal structure of the Leishmania infantum Silent Information Regulator 2 related protein 1: implications to protein function and drug design' PLoS One, vol 13, no. 3, e0193602. DOI: 10.1371/journal.pone.0193602
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