{"id":29578,"date":"2020-06-15T19:05:36","date_gmt":"2020-06-15T19:05:36","guid":{"rendered":"https:\/\/synergy.st-andrews.ac.uk\/cob2\/?p=29578"},"modified":"2020-06-15T19:05:36","modified_gmt":"2020-06-15T19:05:36","slug":"from-single-molecules-to-cells","status":"publish","type":"post","link":"https:\/\/biology.st-andrews.ac.uk\/biophotonics\/2020\/06\/15\/from-single-molecules-to-cells\/","title":{"rendered":"From Single-Molecules to Cells"},"content":{"rendered":"

From Single-molecules to Cells<\/em><\/strong><\/h1>\n

<\/em><\/strong><\/p>\n

Emma Verver, PhD, LUMICKS<\/em><\/h3>\n

1st July, 3.00pm,\u00a0<\/em><\/strong>Microsoft Teams<\/em><\/strong><\/h3>\n

A swiss army knife for high resolution study of<\/strong><\/p>\n

    \n
  • DNA\/RNA-Protein interaction<\/strong><\/li>\n
  • Protein structure & Function<\/strong><\/li>\n
  • Membrane and Cell mechanics<\/strong><\/li>\n
  • Cellular signaling & Transport<\/strong><\/li>\n<\/ul>\n

    Cellular processes are extremely dynamic and ensemble methods of studying these processes fall short in their ability to capture meaningful interactions over the timescales at which these systems operate. Single-molecule methods have proven to be powerful tools towards understanding key processes, such as DNA transcription, membrane dynamics and protein folding.<\/p>\n

    LUMICKS has developed novel biophysical tools to enable the unlocking of biological problems with simple, stand-alone solutions.<\/p>\n

    The C-Trap\u00ae<\/sup> is the world\u2019s first instrument that integrates optical tweezers, confocal (STED) microscopy and an advanced microfluidics system in a truly correlated manner. The C-Trap\u00ae<\/sup> is capable of live, simultaneous and correlative visualization and manipulation of molecular interactions with sub-picoNewton force resolution and sub-nanometer position resolution. It can acquire information with a kilo-Hz (to mega-Hz) temporal resolution, such that even the fastest event can be captured. These abilities of the C-Trap\u00ae<\/sup> allow users to study a wide range of biological mechanisms from single molecules and their complex interactions to single-cell mechanics.<\/p>\n

    The presentation will show that the technological advances in hybrid single-molecule methods can be turned into an easy-to-use and stable instrument that can open new avenues in numerous research areas.<\/p>\n","protected":false},"excerpt":{"rendered":"

    From Single-molecules to Cells Emma Verver, PhD, LUMICKS 1st July, 3.00pm,\u00a0Microsoft Teams A swiss army knife for high resolution study of DNA\/RNA-Protein interaction Protein structure & Function Membrane and Cell mechanics Cellular signaling & Transport Cellular processes are extremely dynamic and ensemble methods of studying these processes fall short in their ability to capture meaningful…<\/p>\n","protected":false},"author":29,"featured_media":29589,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[7],"tags":[],"class_list":["post-29578","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-seminars"],"jetpack_featured_media_url":"https:\/\/biology.st-andrews.ac.uk\/biophotonics\/wp-content\/uploads\/sites\/13\/2020\/06\/Emma-Verver-3.png","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/biology.st-andrews.ac.uk\/biophotonics\/wp-json\/wp\/v2\/posts\/29578","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/biology.st-andrews.ac.uk\/biophotonics\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/biology.st-andrews.ac.uk\/biophotonics\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/biology.st-andrews.ac.uk\/biophotonics\/wp-json\/wp\/v2\/users\/29"}],"replies":[{"embeddable":true,"href":"https:\/\/biology.st-andrews.ac.uk\/biophotonics\/wp-json\/wp\/v2\/comments?post=29578"}],"version-history":[{"count":0,"href":"https:\/\/biology.st-andrews.ac.uk\/biophotonics\/wp-json\/wp\/v2\/posts\/29578\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/biology.st-andrews.ac.uk\/biophotonics\/wp-json\/wp\/v2\/media\/29589"}],"wp:attachment":[{"href":"https:\/\/biology.st-andrews.ac.uk\/biophotonics\/wp-json\/wp\/v2\/media?parent=29578"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/biology.st-andrews.ac.uk\/biophotonics\/wp-json\/wp\/v2\/categories?post=29578"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/biology.st-andrews.ac.uk\/biophotonics\/wp-json\/wp\/v2\/tags?post=29578"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}