{"id":220,"date":"2022-12-01T10:13:31","date_gmt":"2022-12-01T10:13:31","guid":{"rendered":"https:\/\/biology.st-andrews.ac.uk\/research\/?post_type=research_group&#038;p=220"},"modified":"2022-12-21T10:26:37","modified_gmt":"2022-12-21T10:26:37","slug":"mitchell-group","status":"publish","type":"research_group","link":"https:\/\/biology.st-andrews.ac.uk\/research\/research-group\/mitchell-group\/","title":{"rendered":"Mitchell Group"},"content":{"rendered":"<p><span>We are an Informatics and Computational Chemistry research group. Our group is based in the Purdie building on the North Haugh in St Andrews. Research areas we are interested in are machine learning, aqueous solubility, enzyme catalysis, protein-ligand interactions, modelling epidemics, molecular evolution and structural bioinformatics, computational toxicology, prediction of solubility and other molecular properties, and the classification of drugs used for doping in sport.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>We are an Informatics and Computational Chemistry research group. Our group is based in the Purdie building on the North Haugh in St Andrews. Research areas we are interested in are machine learning, aqueous solubility, enzyme catalysis, protein-ligand interactions, modelling epidemics, molecular evolution and structural bioinformatics, computational toxicology, prediction of solubility and other molecular properties, and the classification of drugs used for doping in sport.<\/p>\n","protected":false},"author":76,"featured_media":221,"parent":0,"menu_order":0,"template":"","class_list":["post-220","research_group","type-research_group","status-publish","has-post-thumbnail","hentry"],"jetpack_sharing_enabled":true,"group_members":"<span>John Mitchell;<\/span>\r\n<span>Eugene Shrimpton-Phoenix;<\/span>\r\n<span>Ben Connaughton;<\/span>\r\n<span>Ben Read.<\/span>","publications":"[publications flag='individual' code='jbom' dois='1' max='10' categorise='1']","research_projects":"<ul>\r\n \t<li><span>Combining Theoretical Chemistry and Machine Learning to Understand and Predict Enzyme Function;<\/span><\/li>\r\n \t<li><span>Computational Approaches for Enzyme Redesign;<\/span><\/li>\r\n \t<li><span>Computational Modelling of the Effects of Vaccines;<\/span><\/li>\r\n \t<li><span>Machine Learning for Prediction of Aqueous Solubility.<\/span><\/li>\r\n<\/ul>","related_theme":[{"related_groups":[165,220,239,263],"related_centre":77,"ID":119,"post_title":"Chemical Biology","post_content":"Chemists working at the interface with biology or medicine in the BSRC study, synthesise and modify the small molecules that influence protein function. Using high-throughput techniques and the analysis of bioactive natural products, they develop compounds of medicinal value and gain insights into the mechanism of action of drug molecules.","post_excerpt":"Chemists working at the interface with biology or medicine in the BSRC study, synthesise and modify the small molecules that influence protein function. ","post_author":"4","post_date":"2022-01-21 09:40:59","post_date_gmt":"2022-01-21 09:40:59","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"chemical-biology","to_ping":"","pinged":"","post_modified":"2022-02-25 14:01:22","post_modified_gmt":"2022-02-25 14:01:22","post_content_filtered":"","post_parent":0,"guid":"https:\/\/biology.st-andrews.ac.uk\/research\/?post_type=research_theme&#038;p=119","menu_order":0,"post_type":"research_theme","post_mime_type":"","comment_count":"0","comments":false,"_thumbnail_id":["132","4","2022-02-25 14:01:14","2022-02-25 14:01:14","","IMG_5041-1-scaled","","inherit","open","closed","","img_5041-1-scaled","","","2022-02-25 14:01:14","2022-02-25 14:01:14","","119","https:\/\/biology.st-andrews.ac.uk\/research\/wp-content\/uploads\/sites\/17\/2022\/01\/IMG_5041-1-scaled-1.jpg","0","attachment","image\/jpeg","0","132"],"id":119}],"related_centre":[{"ID":77,"post_title":"Biomedical Sciences Research Complex","post_content":"<span>The\u00a0Biomedical Sciences Research Complex (BSRC) is an interdisciplinary centre for biomedical research with contributions from the Schools of Biology, Chemistry, Medicine, Physics and Astronomy.\u00a0The BSRC's main research themes are infection and immunity, biophysics, molecular medicine, and chemical biology.\u00a0<\/span>\r\n\r\n<a href=\"https:\/\/biology.st-andrews.ac.uk\/bsrc\">Main Website<\/a>","post_excerpt":"","post_author":"4","post_date":"2022-01-17 15:53:50","post_date_gmt":"2022-01-17 15:53:50","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"biomedical-sciences-research-complex","to_ping":"","pinged":"","post_modified":"2022-09-20 13:31:47","post_modified_gmt":"2022-09-20 12:31:47","post_content_filtered":"","post_parent":0,"guid":"https:\/\/biology.st-andrews.ac.uk\/research\/?post_type=research_centre&#038;p=77","menu_order":0,"post_type":"research_centre","post_mime_type":"","comment_count":"0","comments":false,"id":77}],"contact":"<span>jbom@st-andrews.ac.uk<\/span>","_links":{"self":[{"href":"https:\/\/biology.st-andrews.ac.uk\/research\/wp-json\/wp\/v2\/research_group\/220","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/biology.st-andrews.ac.uk\/research\/wp-json\/wp\/v2\/research_group"}],"about":[{"href":"https:\/\/biology.st-andrews.ac.uk\/research\/wp-json\/wp\/v2\/types\/research_group"}],"author":[{"embeddable":true,"href":"https:\/\/biology.st-andrews.ac.uk\/research\/wp-json\/wp\/v2\/users\/76"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/biology.st-andrews.ac.uk\/research\/wp-json\/wp\/v2\/media\/221"}],"wp:attachment":[{"href":"https:\/\/biology.st-andrews.ac.uk\/research\/wp-json\/wp\/v2\/media?parent=220"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}