{"id":242,"date":"2022-12-12T16:12:20","date_gmt":"2022-12-12T16:12:20","guid":{"rendered":"https:\/\/biology.st-andrews.ac.uk\/research\/?post_type=research_group&p=242"},"modified":"2022-12-21T10:16:57","modified_gmt":"2022-12-21T10:16:57","slug":"bela-bode","status":"publish","type":"research_group","link":"https:\/\/biology.st-andrews.ac.uk\/research\/research-group\/bela-bode\/","title":{"rendered":"Bela Bode"},"content":{"rendered":"

The group’s research focusses on using Electron Paramagnetic Resonance (EPR) spectroscopy to study the microscopic structure and dynamics of (bio)molecules and materials.<\/span><\/p>\n

When investigating (bio)molecular structures we often find that the methods available have not been proven to be reliably applicable under the specific circumstances of a given research question. The group embraces the challenge of adapting and implementing EPR methodology to obtain the maximum information content. The ultimate vision is a general approach to determine macromolecular complex structures from EPR data through both long-range interactions between spins and their interactions with their surrounding probing the local chemical environment.<\/span><\/p>\n

In a nutshell, EPR detects the magnetism arising from the \u201cspin\u201d, a quantum mechanical property of unpaired electrons. Although electrons are contained in all matter, they are commonly paired, quenching their magnetism. However, some molecules and materials, such as radicals and paramagnetic metal ions, exhibit unpaired electrons. Using EPR, it is possible to study the unpaired electron and its surrounding through its magnetic spin measuring distances on the nanometre (one billionth of a metre) scale. Over the past 15 years, these distance measurements have developed into an important and powerful method for investigating the nanoworld of large (bio)molecules.<\/span><\/p>\n

http:\/\/chemistry.st-andrews.ac.uk\/staff\/beb\/group\/index.php<\/span><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

The group’s research focusses on using Electron Paramagnetic Resonance (EPR) spectroscopy to study the microscopic structure and dynamics of (bio)molecules and materials.<\/p>\n","protected":false},"author":85,"featured_media":243,"parent":0,"menu_order":0,"template":"","class_list":["post-242","research_group","type-research_group","status-publish","has-post-thumbnail","hentry"],"jetpack_sharing_enabled":true,"group_members":"Dr Katrin Ackermann<\/span>\r\nLaura Remmel<\/span>","publications":"[publications flag='individual' code='beb2' dois='1' max='10' categorise='1']","research_projects":"

\r\n
\r\n
\r\n
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Supramolecular structure predictions validated from sparse experimental data (EPSRC funded)<\/div>\r\n
We are working on various projects contributing long range structural constraints and data on binding affinities to integrative models of biomolecular structure and dynamics underpinning function.<\/div>\r\n<\/div>\r\n<\/div>\r\n<\/div>\r\n<\/div>","related_theme":[{"related_groups":[212,242,263],"related_centre":77,"ID":94,"post_title":"Biophysics","post_content":"BSRC biophysicists study the fundamental molecular structures and interactions that underpin life. Their research spans the structure and molecular mechanism of enzyme function, the interactions between proteins in health and disease, and the mechanics of cell movement.<\/span>","post_excerpt":"BSRC biophysicists study the fundamental molecular structures and interactions that underpin life. ","post_author":"4","post_date":"2022-01-18 01:48:19","post_date_gmt":"2022-01-18 01:48:19","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"biophysics","to_ping":"","pinged":"","post_modified":"2022-02-25 13:58:05","post_modified_gmt":"2022-02-25 13:58:05","post_content_filtered":"","post_parent":0,"guid":"https:\/\/biology.st-andrews.ac.uk\/research\/?post_type=research_theme&p=94","menu_order":0,"post_type":"research_theme","post_mime_type":"","comment_count":"0","comments":false,"_thumbnail_id":["131","4","2022-02-25 13:57:54","2022-02-25 13:57:54","","MB-spreading-histoblast","","inherit","open","closed","","mb-spreading-histoblast","","","2022-02-25 13:57:54","2022-02-25 13:57:54","","94","https:\/\/biology.st-andrews.ac.uk\/research\/wp-content\/uploads\/sites\/17\/2022\/01\/MB-spreading-histoblast.jpg","0","attachment","image\/jpeg","0","131"],"id":94},{"related_groups":[239,242,154],"related_centre":77,"ID":200,"post_title":"Structural Biology","post_content":"","post_excerpt":"","post_author":"4","post_date":"2022-11-28 11:02:10","post_date_gmt":"2022-11-28 11:02:10","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"structural-biology","to_ping":"","pinged":"","post_modified":"2022-11-28 14:31:24","post_modified_gmt":"2022-11-28 14:31:24","post_content_filtered":"","post_parent":0,"guid":"https:\/\/biology.st-andrews.ac.uk\/research\/?post_type=research_theme&p=200","menu_order":0,"post_type":"research_theme","post_mime_type":"","comment_count":"0","comments":false,"_thumbnail_id":["208","4","2022-11-28 14:31:21","2022-11-28 14:31:21","","AdobeStock_257640273","","inherit","open","closed","","adobestock_257640273","","","2022-11-28 14:31:21","2022-11-28 14:31:21","","200","https:\/\/biology.st-andrews.ac.uk\/research\/wp-content\/uploads\/sites\/17\/2022\/11\/AdobeStock_257640273.png","0","attachment","image\/png","0","208"],"id":200}],"related_centre":[{"ID":77,"post_title":"Biomedical Sciences Research Complex","post_content":"The\u00a0Biomedical Sciences Research Complex (BSRC) is an interdisciplinary centre for biomedical research with contributions from the Schools of Biology, Chemistry, Medicine, Physics and Astronomy.\u00a0The BSRC's main research themes are infection and immunity, biophysics, molecular medicine, and chemical biology.\u00a0<\/span>\r\n\r\nMain Website<\/a>","post_excerpt":"","post_author":"4","post_date":"2022-01-17 15:53:50","post_date_gmt":"2022-01-17 15:53:50","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"biomedical-sciences-research-complex","to_ping":"","pinged":"","post_modified":"2022-09-20 13:31:47","post_modified_gmt":"2022-09-20 12:31:47","post_content_filtered":"","post_parent":0,"guid":"https:\/\/biology.st-andrews.ac.uk\/research\/?post_type=research_centre&p=77","menu_order":0,"post_type":"research_centre","post_mime_type":"","comment_count":"0","comments":false,"id":77}],"contact":"beb2@st-andrews.ac.uk<\/span>\r\n\r\nOffice 153<\/span>\r\nPurdie Building<\/span>\r\nNorth Haugh<\/span>\r\nSt Andrews<\/span>\r\nUnited Kingdom<\/span>","_links":{"self":[{"href":"https:\/\/biology.st-andrews.ac.uk\/research\/wp-json\/wp\/v2\/research_group\/242","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/biology.st-andrews.ac.uk\/research\/wp-json\/wp\/v2\/research_group"}],"about":[{"href":"https:\/\/biology.st-andrews.ac.uk\/research\/wp-json\/wp\/v2\/types\/research_group"}],"author":[{"embeddable":true,"href":"https:\/\/biology.st-andrews.ac.uk\/research\/wp-json\/wp\/v2\/users\/85"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/biology.st-andrews.ac.uk\/research\/wp-json\/wp\/v2\/media\/243"}],"wp:attachment":[{"href":"https:\/\/biology.st-andrews.ac.uk\/research\/wp-json\/wp\/v2\/media?parent=242"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}