TKS

Monday 12 December 2022

Research Centre:

Group Highlights

Prof Terry Smith is an expert in phospholipid metabolism and the use of mass spectrometry techniques and heads the Lipidomics Facility with GC-MSs and ABSciex 4000 QTrap for lipidomic and focussed metabolomics. Smith being a joint appointment between Biology and Chemistry also has access to a wide-range of world-class analytical facilities, some of which will be utilised in this proposal, i.e. GC-MS and NMR. Prof Smith has received funding from the Wellcome Trust, SULSA, EU and studentships from BBSRC and MRC. He has more than 27 years’ experience in the molecular and biochemical parasitology arena, including T. brucei, T. cruzi, Leishmania, Toxoplasma and Plasmodium. He has published over 75 papers in the last 10 years, including numerous successful collaborations undertaking lipidomic analyses of various pathogens and numerous models for human diseases.

Research

The Smith group uses their interfacial chemical/biological expertise to find, validate and exploit differences between protozoan and mammalian metabolism.Smith is a leading international authority on parasite lipid metabolism with important publications in this area. His group have to date validated >24 drug targets, conducted several screening campaigns and have 4 lead compound series, which are progressing through the drug discovery pipeline.

Group Members

Dr Louise Major
Dr Farhan Ali
Dr Michela Cerone

PhD students
Jagwinder Dhaliwal
William Mosedale
Veronica Harris
Rachel Humman
Nora Von Xylander
Berta Fatas
Ngoc Anh Thu Trinh
Vytautas Kuodis
Peter Black

M(Res)
Oenone Bodman-Harris

Publications

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Contact

Prof Terry K. Smith CChem, FRSC; FRSB
Director of the Biomedical Sciences Research Complex
University Biological Hazards Adviser
Director of the Cat 3
Radiation Safety Officer
Office B3.10
Biomedical Sciences Research Complex (BSRC),
The North Haugh,
The University,
St. Andrews,
Fife Scotland.
KY16 9ST.
Tel; office: 01334-463412
Email: [email protected]

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