BL4226 – Chromatin and genome stability
BL4226 – Chromatin and genome stability
This module will introduce the fundamental concepts of chromatin structure and function and how this affects genome stability. DNA repair and telomere maintenance are perhaps the most significant factors affecting genome stability and these processes are central to the understanding of cancer cell biology. Indeed, most existing anti-cancer agents induce DNA damage and current efforts to target chromatin factors therapeutically are showing promise. You will have the opportunity to independently research and present seminars on the applied biology of chromatin and DNA repair within model organisms such as budding yeast, Caenorhabditis elegans and Drosophila melanogaster. Students will also have the opportunity to engage in research debates on topics at the forefront of modern cancer biology. Importantly, you will be expected to design and defend a research proposal that addresses an unsolved question of your choice within the field of genome stability.
Skills acquired in this module:
Related Programme(s):
Module Code:
BL4226
Semester:
2
Credits:
15
Module Organiser:
Dr Helder Ferreira
Pre-requisite modules: BL3302 - Gene regulation
MMS
Timetable:
[events_list category="BL4226"]
Assessment:
1.5-hour Written Examination = 25%, Coursework = 75%MMS assessment details
The following related information applies to all Biology modules:
School of Biology Marking Criteria:
School handbook
Late submission of continuous assessment work:
All late submissions of coursework that do not require electronic submission should be made via the late submissions box in the Biology Study Space, St Andrews New Technology Centre Building (beside the Teaching Office)
Exam details:
School handbook
Exam timetable:
Timetable
Expected attendance:
School handbook
Good Academic Practice & Avoiding Academic Misconduct:
School handbook
University Student Handbook:
University student handbook
School and University Regulations:
School and University regulations in the School and University Undergraduate Handbook relating to absence reporting, penalties and rules for late submission of work, extensions for coursework, return of coursework, S-coding, good academic practice and Academic Alerts.
School handbook
University student handbook
Staff:
Learning Outcomes:
Students completing module BL4226 successfully should be able to:
- Evaluate the evidence for and against popular theories in genome stability
- Critically appraise how research problems are tackled experimentally
- Present complex scientic data in a readily understood manner
- Plan and prepare an original grant proposal
Policies:
(Information in this section applies to all Biology Modules)
- The procedures and regulations followed by the School of Biology are outlined in the University Handbook and in the School of Biology Undergraduate Handbook (https://biology.st-andrews.ac.uk/students/wp-content/uploads/sites/6/2022/05/Undergraduate-Handbook-2021-22.docx)
- All coursework associated with the module must be completed and submitted by its due date.
- Specific School regulations relating to absence reporting, penalties and rules for late submission of work, extensions for coursework, return of coursework, S-coding, Good Academic Practice and Academic Alert are stated in the School of Biology Undergraduate Handbook and students are required to carefully read these regulations.
- Students are also referred to the University Handbook, available at:http://www.st-andrews.ac.uk/studenthandbook/